• br Results and discussion br Authorship contributions br Con

  2019-06-20

  

  Results and discussion Authorship contributions Conflict of interest Acknowledgments This work is supported by grants from the United States National Institutes of Health/National Cancer Institute: R01 CA098472 and R01 CA170334. We thank Dr. Dan Zhang and Andy Awwad for technical assista

• br Conclusions br Study limitations br Conflict

  2019-06-20

  

  Conclusions Study limitations Conflict of interest Introduction Dabigatran etexilate, an orally administered pro-drug, is rapidly converted by a serum esterase to dabigatran, a potent, direct, and competitive inhibitor of thrombin. It has an absolute bioavailability of 6.5% and a serum o

• La Constituci n espa ola

  2019-06-20

  

  La Constitución española de 1812 dispone bajo el nombre de América septentrional un territorio que desde California, Nuevo México y Texas hasta la Capitanía de Guatemala conforma una inmensa, compleja y rica estructura administrativa. Guatemala se separa poco antes de la jura de la Constitución de 1

• Sor Juana cuyo genio era para Vigil indudablemente

  2019-06-20

  

  Sor Juana, cuyo genio era para Vigil indudablemente “antimonacal” —recordemos que estamos en pleno periodo posterior PKM2 inhibitor cost las leyes de desamortización de los bienes eclesiásticos— tuvo que tomar una decisión “dictada por las exigencias de su sociedad”, por ello, continúa Vigil, si hub

• Introduction This document does not

  2019-06-19

  

  Introduction This document does not address the indications of genetic testing in patients affected by inherited arrhythmias and their family members. Diagnostic, prognostic, and therapeutic implications of the results of genetic testing also are not included in this document because this topic has

• With respect to the ST elevation in the

  2019-06-19

  

  With respect to the ST elevation in the precordial lead, Antzelevitch et al. demonstrated that this can be an Gap19 of early repolarization or J-wave caused by transient outward current (Ito)-mediated transmural differences in the early phases of the action potential. BS is an inherited disease wit

• The concept of metronomic chemotherapy began in the s

  2019-06-19

  

  The concept of metronomic chemotherapy began in the 1990s, when Kerbel showed chemotherapeutic agents may be able to target tumor vessel endothelial cells. In 2000, Browder et al demonstrated a more frequent, lower dose of cyclophosphamide, i.e. anti-angiogenic schedule, could induce response in tum

• Findings from the last major systematic

  2019-06-19

  

  Findings from the last major systematic review of the global prevalence of echocardiographic rheumatic 7α,25-dihydroxy Cholesterol disease showed that the highest calculated regional prevalence was in sub-Saharan Africa (5·7 cases per 1000 people), indigenous people in the Pacific islands, Australia

• br Uganda is on the verge of eliminating the

  2019-06-19

  

  Uganda is on the verge of eliminating the () form of human African trypanosomiasis (HAT), commonly known as sleeping sickness. This elimination would be historic. In 2015, only four cases of this neglected tropical disease were diagnosed in the entire country. A similarly low number of cases in 2

• br The Millennium Development Goals on

  2019-06-19

  

  The Millennium Development Goals on health have expanded access to basic health interventions to millions of people in low-income and middle-income countries (LMICs). However, access alone will not be sufficient to meet the Sustainable Development Goals (SDGs) if health systems cannot provide high

• br Methods br Results br Discussion For the

  2019-06-19

  

  Methods Results Discussion For the first time, we report the characteristics of meridian acupoint temperatures in healthy medical college students, from which we can construct a meridian acupoint temperature map. The map vividly shows that the acupoint temperature is consistent within a nar

• Paisey et al recently proposed a simple technique for

  2019-06-19

  

  Paisey et al. recently proposed a simple technique for recognizing an MI block. In their study, an abrupt change of the CS activation pattern during RF application, under left atrial appendage pacing from a distal-to-proximal to proximal-to-distal direction provided a reliable assessment of MI condu

• The patient received multiagent chemotherapy using cyclophos

  2019-06-18

  

  The patient received multiagent chemotherapy using cyclophosphamide, daunorubicin, vincristine, predonisolone and l-asparaginase, and high dose MTX/Ara-C, as well as the single-agent administration of nelarabine, hydroxyurea and tyrosine kinase inhibitors (TKIs) (imatinib and dasatinib). The convent

• In recent years there has been growing interest regarding th

  2019-06-18

  

  In recent years, there has been growing interest regarding the role of spliceosome machinery in neoplastic diseases following evidence of the involvement of splicing factor mutations in diverse cancers . (Serine-Arginine Splicing Factor 2) is a member of the serine/arginine (S/A) rich family pre-mR

• Interpretation Stakeholders from sectors not historically en

  2019-06-18

  

  Interpretation Stakeholders from sectors not historically engaged in health care are forming unique partnerships with common goals and a willingness to address the challenge of global cancer care. Funding None. Declaration of interests Abstract Background Since 2013 medical students from North

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