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PPAR plays a critical role in glucose metabolism and
2018-11-06
PPARγ plays a critical role in glucose metabolism and homeostasis (Burns and Vanden Heuvel, 2007). However, the precise molecular mechanisms are still unclear, although previous reports have shown that activation of PPARγ may enhance basal glucose uptake in 3T3-L1 adipocytes (Nugent et al., 2001). O
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Mesenchymal stem cells MSCs can be isolated from
2018-11-06
Mesenchymal stem LY2835219 (MSCs) can be isolated from various adult tissues (including bone marrow), they are multipotent and can differentiate into cells of the mesodermal (e.g. adipocytes, osteocytes, chondrocytes) as well as other embryonic lineages (Jiang et al., 2002). MSCs can also be culture
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br Materials and methods br Author Responsibilities br
2018-11-06
Materials and methods Author Responsibilities Disclosure Study sponsor Acknowledgments We thank Lucy Brown and Alexander Spalla from the Analytical Cytometry Core, Ricardo Zerda and Zhuo Li from the Electron Microscopy Core, and Dr. Xiwei Wu and Charles Warden from the Integrative Gen
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C MYC was found to
2018-11-06
C-MYC was found to act as a driver for the malignant conversion of precursors lesions into HCC (Kaposi-Novak et al., 2009). In fact, HCC, and c-MYC may indeed be responsible for the maintenance and progression of the cancer. This is supported by data of a genetically engineered mouse model in which
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A microsatellite PCR profile has been obtained for
2018-11-06
A microsatellite PCR profile has been obtained for the cell line, and HLA Class I and II typing is available (Table 1). Blood group genotyping gave the blood group O1O1, expected to give rise to blood group O+ (Table 1). The cell line is free from mycoplasma contamination as determined by RT-qPCR.
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br Experimental Procedures br Author Contributions br Introd
2018-11-05
Experimental Procedures Author Contributions Introduction The first prospective study of spinal cord injury (SCI) prevalence in the USA revised the estimated number of individuals living with SCI upward by 5-fold to 1.3 million (Christopher and Dana Reeve Foundation, 2008). The average age
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Flow cytometry can assess cell surface expression of pluripo
2018-11-05
Flow cytometry can assess cell-surface expression of pluripotent markers (e.g., TRA-1-60, TRA-1-81) at the single-cell level and is easily scalable using fluorescent cell barcoding (FCB) (Krutzik and Nolan, 2006). In FCB, each sample in each well is labeled with a different signature, or barcode, of
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The electrical properties of cells were recently analyzed
2018-11-05
The electrical properties of dofetilide were recently analyzed by EIS during the differentiation of stem cells (Angstmann et al., 2011; Bagnaninchi and Drummond, 2011; Venkatanarayanan et al., 2013). These pioneering works have demonstrated a possibility of using changes in impedance as a biomarker
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br Convergence study and computational results To
2018-11-05
Convergence study and computational results To adequately choose the size of the finite elements and the integration step, we examined the convergence of the results as a function of these parameters. Given the physical nature of the simulated vibration process, the grid dimension and the integra
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Calculation scheme According to Buckingham
2018-11-05
Calculation scheme. According to Buckingham\'s theory for a system of two polar components, the following relationships hold true: where ε is the dielectric permittivity; n is the refractive index; V is the molar volume, V= ( is the specific volume; М is the molecular weight); х is the molar fract
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By the middle of the s a series
2018-11-05
By the middle of the 1970s, a series of economic crises replaced earlier trajectories of prosperity and uninterrupted growth with rapidly rising levels of unemployment and declining rates of profitability. This end to the so-called “golden age of capitalism” signaled a fundamental shift both in the
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br Methods br Results Bivariate tests of immigrant concern s
2018-11-05
Methods Results Bivariate tests of immigrant concern scores between whites and non-whites are presented in Table 2. Across all three national surveys, the mean level of immigration concern is significantly higher among whites than among non-whites. Average immigration concern for whites on the
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Due to the lack of knowledge regarding the
2018-11-05
Due to the lack of knowledge regarding the process through which an individual forms a regional identity, in this exploratory study, we suggest that parents contribute significantly to shaping the regional identity of their children: According to socialization theory, as explained earlier, and to t
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br Author Contributions br Conflicts
2018-11-05
Author Contributions Conflicts of Interest Acknowledgments Introduction ADAMs (a disintegrin and metalloproteinases) are multifunctional proteins involved in ectodomain shedding of transmembrane proteins and thereby regulate cell adhesion, migration, and cell–cell communication. Ectodoma
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nmda receptor Previously it was shown th http www apexbt com
2018-11-05
Previously, it was shown that the Wnt1 transcript is strongly induced in MPTP-reactive astroglia, and the release of Wnt1 from these nmda receptor was suggested (L\'episcopo et al., 2010, 2014b; Zhang et al., 2015). Our data show here that Dkk1-mediated blockade of the endogenous Wnt/β-catenin path
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