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We have developed a Clinical Laboratory Improvement
2018-10-30
We have developed a Clinical Laboratory Improvement Amendments (CLIA)-approved, high-throughput, genotyping platform to determine the cdc42 pathway status of a large panel of known cancer genes. The mutation detection protocol, SNaPshot, uses a highly sensitive multiplexed polymerase chain reaction
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Conflicts of interest br Introduction The goal
2018-10-30
Conflicts of interest Introduction The goal of islet transplantation is to use the donor β-cells to restore the insulin production and glycemic regulation in patients with type 1 diabetes to avoid serious complications (Barton et al., 2012; Goland and Egli, 2014). For long-term graft survival, n
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br Materials methods br Results br Discussion The overall
2018-10-30
Materials & methods Results Discussion The overall purpose of the study was to scrutinize the development of the CH58 antibody from its germline precursor in the context of understanding V2 immonogenic responses. The increased affinity of the mature CH58 antibody over its inferred unmutated
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We chose to study mAb because it is a potent
2018-10-30
We chose to study mAb41 because it is a potent neutralizing antibody that arises from an antigenic region that can induce both neutralizing and non-neutralizing antibodies, providing a basis for investigating whether mAb41 mimotopes could induce immune responses with mAb41-like properties, including
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order Solamargine In the present study we aimed at integrati
2018-10-30
In the present study we aimed at integrating single cell properties and network activity in dissociated cultures of Ts65Dn and Tc1 mouse models and in their respective diploid cultures. We report here that network activity was reduced and that trisomic neurons were less excitable due to an increase
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Previous in vitro studies using type strains and monoculture
2018-10-30
Previous in vitro studies using type strains and monocultures of bacterial pathogens have shown cysteamine to have direct antimicrobial activity with MIC100 at concentrations in the range of 250–500μg/ml (in nutrient rich media) against P. aeruginosa and other CF pathogens including Burkholderia cep
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br T memory stem cells T a rare subset of
2018-10-30
T memory stem 4-ethylphenyl sulfate (T), a rare subset of memory lymphocytes endowed with enhanced capacity of self-renewal and the potential to reconstitute the full repertoire of memory and effector cells, have recently emerged as a central player in several physiological and pathological proces
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Tissue top down microproteomics gives insight on
2018-10-29
Tissue top-down microproteomics gives insight on the tumor microenvironment with the identification of proteins involved in cancer processes, diagnosis and/or progression (Table 1). For example, the C-terminal fragment (aa425–483) of Cytokeratin-8 (KRT8) has been detected in our experiments in the n
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For each of the rHSA samples approximately g
2018-10-29
For each of the rHSA samples, approximately 10µg were diluted in 50mM ammonium bicarbonate to a total volume of 200µl. To each solution 10µl of 250mM dithiothreitol (DTT) in 50mM NH4HCO3 were added followed by incubation for 1h at 60°C. Next, 20µl of 250mM iodoacetamide in 50mM NH4HCO3 were added an
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br Acknowledgments This work was
2018-10-29
Acknowledgments This work was supported by National Natural Science Fund of China (Grant no. 61375079). Data The subsequent 52 files are for the specific environmental conditions, under which the six layer configurations are examined. The 52 files are the production of 13 climates and four oc
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Only two studies have investigated whether pubertal factors
2018-10-29
Only two studies have investigated whether pubertal factors also influence white matter microstructure in adolescence, in addition to effects of age. The first study looked at RD in white matter tracts in males and females aged 8–28 years (n = 114, 63 females), and explored whether pubertal effects
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If children s sensitivity to the syntactic contexts of
2018-10-29
If children\'s sensitivity to the syntactic contexts of nouns and verbs is so robust, then how did they acquire this knowledge? In other work, we explored the possibility that children bootstrap into the abstract categories of their language by initially relying on a small number of highly frequent
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simvastin The specimens for transverse tensile test and SCC
2018-10-29
The specimens for transverse tensile test and SCC tests were extracted from the parent metal and weld joints using wire-cut electric discharge machining. The tensile properties of as-received parent metal and weld joints are listed in Table 2. In order to reveal the susceptibility of Super 304H pare
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Sin embargo aunque las integrantes de catw
2018-10-29
Sin embargo, aunque las integrantes de catw y otras abolicionistas feministas consideran que es imposible que una mujer acepte por voluntad propia ofrecer servicios sexuales y que por lo tanto todas las migrantes que se prostituyen (y más bien todas las prostitutas, sean o no migrantes) son víctimas
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N6022 De la misma forma es
2018-10-29
De la misma forma, es importante señalar, como hace Carby (2008, p. 92), que el concepto patriarcado, aplicado N6022 diversos tipos de situaciones coloniales, es insatisfactorio; no permite explicar, por ejemplo, por qué los hombres negros nunca tuvieron los beneficios del patriarcado blanco y por q
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