• Introduction Klebsiella pneumoniae a Gram negative

  2020-04-03

  

  Introduction Klebsiella pneumoniae, a Gram-negative enteric bacterium, is an organism with significance in both biomedicine and biotechnology. Some of the strains of K. pneumoniae are opportunistic pathogens, which can cause suppurative infection, pneumoniae and urinary tract infection in humans (B

• Our recent QTL mapping study revealed that the adaptor genes

  2020-04-03

  

  Our recent QTL mapping study revealed that the adaptor genes, including the NCK genes and the ABI genes, are located within the genomic regions harboring the most significant QTL (Zhou et al., 2017), suggesting that these genes could be involved in the determination of resistance, and possibly throu

• Although BPA has been proven to cause

  2020-04-03

  

  Although BPA has been proven to cause many health issues such as obesity and neurological toxicity (Rubin, 2011), the effects and mechanisms of BPA on the human tumorigenesis and cancer development are still not well illustrated. In the present study, we found that 10 to 10M BPA significantly promot

• br Conflict of interest statement br

  2020-04-03

  

  Conflict of interest statement References and recommended reading Papers of particular interest, published within the period of review, have been highlighted as: Acknowledgements We acknowledge financial support by the Swiss State Secretariat for Education, Research and Innovation (Federal

• The main advantage of exploiting paper

  2020-04-03

  

  The main advantage of exploiting paper sludges as sources of cellulose-derived energy and chemicals in comparison to other lignocellulose substrates is their amenability, which is associated with an extensive pulping process that removes the majority of the lignin and exposes Cefepime Dihydrochlorid

• Mulan is one of three E

  2020-04-03

  

  Mulan is one of three E3 ubiquitin ligases that are present in the mitochondria along with MARCH5/MITOL (membrane associated RING-CH5) and RNF185 [14], [15], [16], [17]. Mulan is a 352-residue polypeptide that crosses the mitochondrial outer membrane (OMM) twice, its amino-terminus, which includes t

• br Significance Dysregulation of dopamine

  2020-04-03

  

  Significance Dysregulation of dopamine homeostasis contributes to Parkinson\'s disease (PD). The nuclear receptor Nurr1 plays a central role in dopamine homeostasis, regulating the transcription of MK-4827 governing the synthesis, packaging, and reuptake of dopamine. Efforts to capitalize on Nur

• A range of inhibitors were

  2020-04-03

  

  A range of inhibitors were therefore synthesized containing either carboxylic NHS-12-Biotin or ester functionality at the ‘tail’ group as well as variations in the ‘head.’ These were assayed in vitro using the DCIP assay for binding affinity against and human DHODH at 50μM, respectively (). Analy

• Within the Class II receptors

  2020-04-02

  

  Within the Class II receptors, the Type I IFN receptor subunit, IFNAR-1, is exceptional in having four tandem FNIII domains, denoted here D1–D4. This structure appears to have arisen as a tandem orbifloxacin of the basic D1/D2 structure; thus, D1 and D3 of IFNAR-1 are more closely related, as are D2

• Experiment Blunted fear potentiated startle due to

  2020-04-02

  

  Experiment 2: Blunted fear-potentiated startle due to deficient fear acquisition. SERT+/+ and SERT+/− showed significant acquisition of the cue-shock association, whereas SERT−/− did not (trial×genotype interaction: F2,50=3.3, papigenin of fear-potentiated startle. Acquisition: Following fear acqu

• br Method br Results br Discussion In this

  2020-04-02

  

  Method Results Discussion In this cross-sectional study, we investigated the relationship between the COMT ValMet polymorphism and age on regional cortical thickness in healthy adults across the lifespan. The mesocortical pathway was of primary interest because of its projections from the v

• Early studies from the mollusk Aplysia reported the

  2020-04-02

  

  Early studies from the mollusk, Aplysia, reported the presence of a unique class of YAP-TEAD Inhibitor 1 synthesis receptors in neurons, the acetylcholine-gated chloride channels (ACCs) (Kehoe and McIntosh, 1998). Later, studies identified these receptors in the model nematode Caenorhabditis elegan

• Gemcitabine HCl receptor In the present study cells were exp

  2020-04-02

  

  In the present study, cells were exposed to a low level of arsenite and a low cytotoxic concentration of BaP. Thus, γ-H2AX loss correlated with repair of DNA damage in cells co-exposed to arsenite and BaP. These results show that arsenite inhibits repair of BaP-induced DNA damage. In a previous stud

• We continued to investigate the contribution of the

  2020-04-02

  

  We continued to investigate the contribution of the EP1 5-(N,N-dimethyl)-Amiloride hydrochloride to nociceptive sensitization by utilizing its natural ligand PGE and tested the effect of local subcutaneous injection of PGE (5nmol in 5μl) into one hindpaw on mechanical and heat pain thresholds. Wild

• br Experimental Procedures br Author Contributions

  2020-04-02

  

  Experimental Procedures Author Contributions Acknowledgments We acknowledge Géraldine Le Goff and Mathieu Canales for blood sampling, Cécile Gameiro and Jean-Pierre Aubry for flow cytometry technical assistance, Giuseppe Pantaleo for support, and Britta Engelhardt, Gisella Puga-Young, Nicol

15988 records 851/1066 page Previous Next First page 上5页 851852853854855 下5页 Last page